The Laboratory of Experimental Pathophysiology was created in 2002 and is linked to the Post-graduate Program in Health Sciences (PPGCS) of University of Southern Santa Catarina (UNESC).

The main objective of the research group is to study the biological mechanisms of disease, in order to understand its evolution and to develop better therapeutic strategies. To do so, relies on experimental, preclinical, clinical and epidemiological studies. The involvement of oxidative stress and metabolic and immunological diseases in the development has been highlighted in our research. In addition, the group develops new treatment protocols from native plants of our region, to be tested for their effectiveness in animal models of several diseases. The projects are funded by development agencies such as the National Council for Scientific and Technological Development (CNPq), Coordination for the Improvement of Higher Level Personnel (Capes) and the Foundation for Support of Scientific and Technological Research of the State of Santa Catarina (Fapesc).

The Laboratory of Experimental Pathophysiology is composed of faculty researchers, students of the Graduate Program in Health Sciences (PPGCS) of UNESCO in the Masters and PhD level, undergraduate students and students volunteer trainees.

Our research group also has the collaboration of other researchers, like Prof. José Cláudio Fonseca Moreira and Prof. Fábio Klamt, from the Center for Studies in Oxidative Stress, and Prof. Angela Terezinha de Souza Wyse, Laboratory of Inborn Errors of Metabolism. Both are linked to the Post-graduate Program in Biochemistry of Federal University of Rio Grande do Sul. Another collaborator is Prof. Jamil Assreuy, from the Post-graduate Program in Pharmacology of Federal University of Santa Catarina.